| Place Name | Cape Girardeau |
| Place Type | City |
| ZIP Code(s) | 63701 63703 |
| County | Cape Girardeau County Scott County |
| Area Code(s) | 573 |
| Timezone | Central Standard Time (CST) |
| Population (2022) | 37,982 |
| Population Growth Rate (2010-19) | 4.21% |
| Majority Ethnicity | White 79.35% |
| Metro/Micro Stats Area | Cape Girardeau, MO-ILSikeston, MO |
| US Congressional District(s) | Missouri 8th |
| State House Districts | 146,147,148 |
| State Senate Districts | 27 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 79.35% |
| African American | 13.94% |
| Hispanic | 0.11% |
| Asian | 2.9% |
| Native American | 0.17% |
| Hawaiin/Pacific Islander | 3.53% |