| District Name | Poplar Bluff R-I School District |
| State | Missouri |
| County | Butler County |
| Statistical Area | Poplar Bluff, MO |
| Total Students (2021) | 5137 |
| District Growth Rate (2017-21) | -4.7% |
| Majority Race/Ethnicty | White (79.3%) |
| Free/Reduced Lunch Program | 78.33% |