| Place Name | Big Pine Key |
| Place Type | Census Designated Place |
| ZIP Code(s) | 33043 |
| County | Monroe County |
| Area Code(s) | 305,786 |
| Timezone | Eastern Standard Time (EST) |
| Population (2022) | 3,777 |
| Population Growth Rate (2010-19) | 6.33% |
| Majority Ethnicity | White 83.38% |
| Metro/Micro Stats Area | Key West, FL |
| US Congressional District(s) | Florida 26th |
| State House Districts | 120 |
| State Senate Districts | 39 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 83.38% |
| African American | 0.48% |
| Hispanic | 0% |
| Asian | 0.66% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 15.48% |