| Place Name | Mayo |
| Place Type | Census Designated Place |
| ZIP Code(s) | 29368 |
| County | Spartanburg County |
| Area Code(s) | 864 |
| Timezone | Eastern Daylight Time (EDT) |
| Population (2022) | 1,359 |
| Population Growth Rate (2010-19) | -1.57% |
| Majority Ethnicity | White 96.27% |
| Metro/Micro Stats Area | Spartanburg, SC |
| US Congressional District(s) | South Carolina 5th |
| State House Districts | 32 |
| State Senate Districts | 14 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 96.27% |
| African American | 0% |
| Hispanic | 0% |
| Asian | 1.96% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 1.78% |