| Place Name | Puxico |
| Place Type | City |
| ZIP Code(s) | 63960 |
| County | Stoddard County |
| Area Code(s) | 573 |
| Timezone | Central Daylight Time (CDT) |
| Population (2022) | 767 |
| Population Growth Rate (2010-19) | -0.91% |
| Majority Ethnicity | White 99.81% |
| US Congressional District(s) | Missouri 8th |
| State House Districts | 151 |
| State Senate Districts | 25 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 99.81% |
| African American | 0.1% |
| Hispanic | 0% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 0.1% |