| Place Name | Karnes City |
| Place Type | City |
| ZIP Code(s) | 78118 |
| County | Karnes County |
| Area Code(s) | 830 |
| Timezone | Central Daylight Time (CDT) |
| Population (2022) | 3,090 |
| Population Growth Rate (2010-19) | 2.27% |
| Majority Ethnicity | Hispanic 0.14% |
| US Congressional District(s) | Texas 15th |
| State House Districts | 17 |
| State Senate Districts | 21 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 47.17% |
| African American | 4.41% |
| Hispanic | 0.14% |
| Asian | 0.08% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 48.19% |