| Place Name | Santo Domingo |
| Place Type | Comunidad |
| ZIP Code(s) | 00624 |
| County | Penuelas |
| Area Code(s) | 787,939 |
| Timezone | Atlantic Standard Time (AST) |
| Population (2022) | 3,011 |
| Population Growth Rate (2010-19) | -6.31% |
| Majority Ethnicity | Hispanic 0% |
| Metro/Micro Stats Area | Yauco, PR |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 33.26% |
| African American | 4.46% |
| Hispanic | 0% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 62.27% |