| Place Name | Mayesville |
| Place Type | Town |
| ZIP Code(s) | 29104 |
| County | Sumter County |
| Area Code(s) | 803 |
| Timezone | Eastern Daylight Time (EDT) |
| Population (2022) | 560 |
| Population Growth Rate (2010-19) | -25.03% |
| Majority Ethnicity | African American 86.15% |
| Metro/Micro Stats Area | Sumter, SC |
| US Congressional District(s) | South Carolina 6th |
| State House Districts | 64 |
| State Senate Districts | 36 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 13.85% |
| African American | 86.15% |
| Hispanic | 0% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 0% |