| Place Name | Santa Isabel |
| Place Type | Zona Urbana |
| ZIP Code(s) | 00757 |
| County | Santa Isabel |
| Area Code(s) | 787,939 |
| Timezone | Atlantic Standard Time (AST) |
| Population (2022) | 6,216 |
| Population Growth Rate (2010-19) | -9.04% |
| Majority Ethnicity | Hispanic 0.23% |
| Metro/Micro Stats Area | Santa Isabel, PR |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 20.02% |
| African American | 16.9% |
| Hispanic | 0.23% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 62.85% |